Science of Synthesis

When you are developing synthetic organic routes, Science of Synthesis (SOS) is the optimal resource that offers you the best methods and, therefore, the best results.

The coverage of synthetic methods in SOS is highly structured and systematically, logically, and consistently organized for each functional group. You can quickly get an overview of the different methods available to achieve a transformation and find out which methods are useful for a particular synthesis and which are not.

Science of Synthesis is a valuable teaching and learning resource for all areas of synthetic organic chemistry. The knowledge platform offers you in-depth information and is ideal for helping you find key examples of reactions to include in lectures and courses, as well as for advanced studies and further reading around a topic. In addition, many of the reference library topics include didactic coverage of basic principles and concepts in the field, providing an ideal introduction to the area.

The content of Science of Synthesis is available in three different “aggregate states”. Depending on your needs, you can explore its wealth of knowledge either via the SOS Online Platform or within the SOS eBooks. Alternatively, you can use the SOS Reaction Datasets, where all the structures and reactions are in machine-readable format that can be used for cheminformatics applications, such as training algorithms.

SOS Datasets: Science of Synthesis Knowledge in Machine-Readable Format

The international editorial board of Science of Synthesis features world-renowned chemists from industry and academia. It is chaired by Executive Editor Prof. Erick M. Carreira.

Since 1909, hundreds of experienced chemists have been responsible for publishing Houben-Weyl and Science of Synthesis, and this tradition continues to this day.

The Science of Synthesis Early Career Advisory Board (ECAB) is a three-year program designed for young chemists. Science of Synthesis invites early-career researchers to apply to join the SOS ECAB. As a member of the ECAB, you get the exclusive opportunity to influence the future of chemistry, expand your network, and gain exclusive access to resources and events.

Download the Science of Synthesis brochure, MARC records, and title list and learn more about product access and account usage statistics.

Would you like to find out how Science of Synthesis can benefit your research or help others at your institution? We can easily arrange a free trial for your institution, accompanied by a live demonstration, showing you how to make the most of SOS.

More than 2,500 organic synthesis experts from around the world have contributed to Science of Synthesis. Among them are some renowned chemists and researchers from the organic synthesis community who have won the Nobel Prize:

Science of Synthesis is a multi-author reference work. Contributors are individually invited by our volume editors, who select authors based on their specialized knowledge and expertise in a given area of chemistry.